April 29, 2025

Episode #547: Perspectives on Longevity-Opportunities, Obstacles, and Gabriel Cian's Mission

Episode #547: Perspectives on Longevity-Opportunities, Obstacles, and Gabriel Cian's Mission
HALO Talks: Elevating Wellness
Episode #547: Perspectives on Longevity-Opportunities, Obstacles, and Gabriel Cian's Mission

On this episode of HALO Talks, host Pete Moore sits down with Gabriel Cian, a serial entrepreneur from France with a passion for longevity and health innovation. Gabriel shares his journey from building and successfully exiting two tech startups to founding the 2060 Foundation, an organization dedicated to advancing longevity through investment and policy change. The conversation dives further into the intricacies of selling a company, the booming field of longevity science, and the crucial roles of healthspan, lifespan, and mental health in extending quality of life.

Gabriel and Pete also discuss the challenges and opportunities facing entrepreneurs in this space, the global landscape of longevity policy, and how his foundation is helping drive change through investment and advocacy. Whether you're a startup founder, investor, or simply curious about the future of human health and well-being, this episode is packed with insights and inspiration from one of the leading voices in the field.

When it comes to the aging process, Cian states, "We are trying to slow it down, stop it, or even, let's be crazy, reverse it! And this is more science fiction-like. It's more futuristic, and it's certainly riskier as a business model."

Key themes discussed

  • Serial entrepreneurship and successful tech company exits.
  • Structuring and achieving earn-outs during company acquisitions.
  • Transition from tech to longevity and health span focus.
  • The mission and activities of the 2060 Foundation.
  • Importance of mental health and social connections in aging.

A few key takeaways:

1. Career Pivot to Longevity: Gabriel built and successfully exited two tech startups (including getemail.io), primarily in AI, big data, and marketing automation. After his last exit in 2021, he shifted his focus entirely to the field of longevity, dedicating the next chapter of his life to helping people live longer, healthier lives.

2. Longevity Ecosystem: Healthspan vs. Lifespan
Gabriel outlined two "ecosystems" within longevity:

Healthspan: Practical, current interventions like physical activity, nutrition, sleep, stress management, and proven supplements.
Lifespan: The science-driven, experimental side aiming to understand and potentially slow or even reverse aging at the biological level—an area that's more risky but with potentially greater breakthroughs.

3. The 2060 Foundation's Unique Model: His 2060 Foundation is structured to bridge short-term and long-term solutions. In the short-term, they're building startups focused on healthspan (which investors and VCs more easily understand.) The profits and expertise from those support longer-term, riskier projects—like advocating for legal and regulatory changes and funding true lifespan-extending science.

4. Investment Club Approach: A core project of the 2060 Foundation is an investment group made up of entrepreneurs passionate about longevity. Their aim is to funnel more capital and mentor talent into both healthspan startups and true longevity biotech, without seeking profit for the foundation itself.

5. Policy, Prevention, and Advocacy
Gabriel emphasized two roadblocks to progress in longevity: Governments' reluctance to fund true "preventative" healthcare versus reactive "sick care", and the fact that aging isn't classified as a disease on a global medical level, which limits research funding.

Resources:

Transcript
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wizard. Go get them.

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This is Pete Moore on Halo Talks. I have the pleasure of bringing from

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international base of South Of France, Gabriel

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Sian. We're gonna talk about longevity. We're gonna talk about

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his serial entrepreneurship in the technology space,

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and he has sold two businesses and going to build

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several more in the future. So, Gabriel, welcome to your first Halo

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Talks. Yeah. Thank you so much for having me here.

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Awesome. So give us a little background on what you've done,

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some of the startups that you turned into companies that exited, and then

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talk about why your passion and, energy is going to lie

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in, in helping new companies. Yeah. So thank you

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very much for for the intro. I've been entrepreneur for the last twenty

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years coming from the tech space, and I have created a couple

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of startups, sold two of them, in the tech

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space with artificial related to artificial intelligence, big data,

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and marketing automation most of the time. Good. So,

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I exited the last one in 2021. At that time, I was 40 years

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old. And I decided to,

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change completely gears and focus on longevity on

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the last half of my life, so to speak. I have discovered

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longevity. There there are this is a new universe which is so

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fascinating. The science is moving

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forward so quickly, and the prospects of living longer

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and healthier was very enticing to me, and I

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just wanted to devote the rest of my, you know, energy and life

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to to longevity, helping people live as long as healthy and

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healthy as possible. So, you know, tell us about the, you know,

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getgetemail.i0 and then Prague online

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and, you know, what you did on those two companies that

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you think were, you know, game changers, or what what pivot you

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do you into having the ability to have somebody come and wanna

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acquire businesses? Because as most entrepreneurs know, you know,

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90% of companies that get started do not get acquired.

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Absolutely. As for a very tough business, a very

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tough universe to be in, and a very tough,

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activity on a daily basis to make. Those, out of

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those company successes that acquirers would be

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interested into acquiring. So by the way, in

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2021, yeah, the company was acquired by a big US

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publicly traded corporation called Dun and Bradstreet.

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And it was a great experience for me

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to sell the company and also work

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for two years, for the earn out and the

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transition period before between, you know,

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to make to make sure that things happen, on the right side for

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for the acquirer. Got it. So what I've done what what I've done

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I've done differently. To be honest, it's it's a it's a software as

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a business universe. So

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in SaaS businesses, actually, it's it's it's pretty

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hard to to to to, be successful.

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You need to execute really well. You need to say no

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to many opportunities because at some point, everybody's going to ask this

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feature and that feature. And if you get lost into that kind of complexity,

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you're out of business at some point, or you're going to suffer a

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burnout or anything, but you're not going to be successful. So saying no

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to so many opportunities and just laser

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focus on one thing and doing the best in the world, I think

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was a game changer for us and for the industry as a whole. Another

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question is, in my previous company,

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I was very much focused on the local market, the

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French and French speaking market. But the world is much

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bigger than that. So for getemail.io, what I said is that for

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day one, I would focus and consider that the whole world

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is is our playground. And it has been a game

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changer also because we opened up to a market

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that was, like, worldwide. And after a year or

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so, we had more customers in The United States than in

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our home country. Gotcha. Great.

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So let's talk. You mentioned that part of the consideration

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that was paid was an earn out, and and, you know, a lot of the

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people that listen to Halo talks and that I've interacted with has

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been to educate them on deal structure, educate them on financials,

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how do you value businesses. So for those people that don't know, you

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might get paid a certain amount upfront. Let's say you got 5,000,000 upfront,

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but you really wanted $8,000,000 for the business, and the company was willing to

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pay you 8. But they're like, look. You gotta earn your way out of this

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deal, and you gotta produce. And then I'll pay you a

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prescribed dollar amount if you do earn out and actually achieve

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what we agree that you're going to achieve either twelve months or twenty four

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months down the road in the future. That may be

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under my my control, but your benefit, or I might give you

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some control over that outcome by letting you run your business

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inside of my business. So could you talk for a minute or two about,

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you know, maybe not the exact economics, but how you develop the earn out

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formula so people know about that, and then how you go

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about making sure that you collect it? Yeah. Absolutely. So it's a

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very tricky issue, to be honest, because the the acquirer

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has, control over your your company, what was your

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company. But at the same time, you're supposed to

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deliver some, tangible results. So

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it's a middle ground that is not easy to to cope with.

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So what happened to us was that, the acquirer

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was intelligent enough and and good willing to

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help us and to put the resources in front of the, you

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know, the goal we were supposed to, to reach. And

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we were successfully able to reach those milestones

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and to get the earn out. But, again, I

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was one of the very few people,

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in my in my network who sold their company

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and was able to reach those milestones and and get their

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earn out at least fully. So so and then from a

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standpoint of the company paying the earn out, was

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it a complicated formula? Was it just, hey. Here's my revenue. Here's

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my members. Here's my customer base. I've done somewhere else where I've tried

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to to pin it on the highest

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denomination, basically. Like, revenue is hard to manipulate and

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argue about. Number of customers hard to manipulate and argue about a certain

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day. EBITDA, you know, I can layer a lot of cost into your

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business that we might argue was my cost. You might

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argue was your cost. We might not be that willing as

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a buyer to, like, just stroke a check to you again because I I already

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thought I paid a fair value for your company. Quite frankly, I didn't think we

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you're gonna hit the earn out. Yeah. So, honestly, the formula was

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pretty simple. But the way,

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the words that the the lawyers our lawyers, put

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it, it was a nightmare. I I really only

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trusted them that they would do the work for us, and and,

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honestly, I was right to do so. But it was very complex, very

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simple to understand, and very complex to read and and and then

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try to imagine what it is if you didn't knew it know it in in

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first place. Yeah. So so so buyer beware or

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seller beware on try to get as much money upfront as you

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can on a sale. Make your earn out achievable

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and make it based on a number that is

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the hardest number for either side to potentially

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manipulate or take take a counter view. And I do

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agree with you that the the language in a, in a

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purchase agreement on earn outs should be a

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picture and an Excel financial model. I try and get a

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financial model of outcomes. So it's harder to

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manipulate what what the launch meant is actually in the exhibit.

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So thank you for sharing that that knowledge. Welcome. So

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so so you sold the business. Now you got something called twenty sixty

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foundation. Talk about what that is. Yeah. So,

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because I have decided to devote, you know, the rest of my life to

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to longevity, I really wanted to put

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the, the foundations of, of what I

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was about to to, to execute. And

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in longevity, you have two sub ecosystems, I would say. You

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have the health span ecosystem and the life span ecosystem. The

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health span ecosystem is about things that you and I can do,

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and and it's state of the art with what we know to do today

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in medicine. Right? It's about healthy

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living. It's about taking care of your diet. It's about taking some

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medications, some some supplements, things that are very practical.

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One of the the flagships, in in in in

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this ecosystem is, a doctor called Peter Attia.

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And he's really very realistic with what we can

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do and trying to give very practical insights into

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how to take care of one's health considering

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what is known today in medicine. And then you have

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the the lifespan ecosystem where we are trying

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to understand at the biological level how, the

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process of aging is working, and we are trying to fiddle with it. We

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are trying to, slow it down, stop it, or

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even, let's be crazy, reverse it. And this is

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more science fiction like. It's more futuristic, and

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it's riskier as a business. And the people who are,

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really, working in the field are really trying

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to disrupt the field with breakthroughs scientific

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breakthroughs. So you have those two ecosystems. So for me,

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I understood that as population is getting older and older,

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you need to create startups on the health span

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field, right, universe. Because businesses,

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investor investors understand this. You have a a

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path to profitability that are pretty short term with which is

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compatible with what venture capital is looking for today. And you

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need to use those companies and the

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profit to invest into a foundation, which is called two thousand and

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sixty, the two thousand and sixty Foundation that is going to take care of long

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term projects that the venture capital doesn't know how to deal with. Like

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for example, changing laws. There are two categories of laws

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that are not working right in the world and are not longevity

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compliant today. One of them is how do we spend money on preventative

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medicine? In many countries, you don't have,

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health care. We have you have sick care, which means that

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people are getting sick. And at that point, the

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state is going to give them some subsidies and their their insurance

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policy, health policy is going to a fund for

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the treatment. But you have to take care way before that

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happens, right? And you want to change that. You

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want governments to spend money on preventative health

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instead of curative health. So that's one

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thing. And you need to change laws about this. And it's taking a a a

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lot of time and and somebody has to do it. And second

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point is, as strange as strange as it may seem,

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aging is not considered a disease. So the huge amounts of

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public funding that goes today into research against

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cancer, against cardiovascular disease, against neurodegenerative

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disease, against metabolic, syndromes

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doesn't go into the the root cause of all those

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chronic diseases, which is the process of aging itself.

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So you need to get into the WHO

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disease classification and adds a category

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called age related diseases or aging altogether. So in order

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to change those two things, you need a foundation to take care of,

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of the long term projects related to longevity.

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This is Pete Moore. I wanna let you in on a little secret. There's this

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company called Promotion Vault, and what they do is they give out rewards

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from retailers that allow you to incentivize your

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members without having to do zero down and one month

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free or giving away shakes or giving away T shirts. What

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you wanna do is build a rewards program that lasts, that

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people value, and that doesn't discount your own products and services.

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So here's the deal. There's something called rewards vault. The rewards

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vault is going to allow a member to set up their own profile.

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They are going to answer questions. You are gonna get those answers. You're gonna be

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able to target those members, and you're gonna reward them inside your

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club, inside your spa, and outside of the club, and outside

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of the spa to get them to become loyal, to get them to pay

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their monthly dues, and to be rewarded properly for

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the actions. A lot of companies are cutting back on rewards. You shouldn't

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be. Promotion Vault's your answer. Trust me. This is

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real. So let me

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ask you a question. So twenty sixty foundation as it's

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set up right now seems to me, and correct me if I'm

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wrong, is it's really a a, a lobbying

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slash movement of trying to get awareness

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and potential investment into companies that are

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solving these problems, and hopefully they come up with a solution.

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But are you, like, what hat are you wearing? Are you,

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like, a potential investor in in businesses

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once you get them kind of green lighted through where they could

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become commercialized? Are you more of a,

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public advocate? And you're saying, hey, I'm not necessarily looking to make

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money at two thousand and sixty Foundation as like the

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owner or entrepreneur or protagonist behind

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it. And I wanna be known as like, hey, I'm like the head of like,

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you know, I kinda cling to myself like I'm like Captain Halo, like I'm a

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superhero trying to get capital into The US market

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and global market for these types of companies that will in

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return will solve some component of

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solving low loneliness, obesity, or diabetes. So

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where do you kinda sit when you wake up in the morning? Are you the

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CEO of what? Yeah. So so

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listen. For for 2060, the the flagship project we

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are working on right now is an investment club

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where we bring investors, most of them folks like me who have

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sold companies and are really interested into longevity. And

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some of them are financing the longevity startups, both health

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span and lifespan, like the biotech crazy stuff. Some of

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them are creating, companies around

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longevity topics. Again, either

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biotech or the more health aspects of it. So we

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are really trying to grow the the amount of money that is being

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invested into longevity, and and and

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also trying to inspire as many entrepreneurs as

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possible to start new companies in this, in this

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field. Gotcha. So that's the If you want yeah. If you wanna use the

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term halo to your twenty sixty foundation, I hereby

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bequeath the use of the term halo, health, active lifestyle

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outdoors, because that's really the foundation of Yeah. Solving all these

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chronic diseases in The US. That's why we we use it instead of the word

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wellness, because you have to create the halo effect.

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Yes. No pressure. I'm just giving it I'm giving it to you because it's royalty

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free. We want everyone to use it. So Great. Thanks. Thanks so much.

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Feel free. So so as you okay. So now I get it. So I got

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an investment club that's basically trying to pressurize certain

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things in the market that could be game changers. If you take

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a look at let's let's use Ozempic or we get Wegovo,

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or any of these GLP one drugs as, you

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know, longevity, instigators, we'll call. Right?

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If I could change the way you behave Absolutely. Then then I'm part of the

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longevity, you know, twenty sixty curve. You better get to the gym also

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or else you're gonna wither away. So how do you

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view weight loss and maybe certain things that might be

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deemed like, oh, that's a fast track for you to, like, lose weight,

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not the, you know, the traditional way of, like, I earned it, you

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know, necessarily? Yeah. Yeah. Absolutely. So so what

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people need to know is that, all those miracle pills have

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secondary effects have side effects. So it's not only you lose weight.

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You you have there is a price to pay. I'm not I'm not talking about

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financial price necessarily, but also a price in terms of side effects

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of risk. So today, longevity is

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about five, categories of interventions.

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You have, physical activity. You have diet.

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You have sleep. You have, mental health, stress

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management, and, related issues. And last but not

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least, supplements and some drugs that

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we use even, you know, for preventative reasons. So

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when you when you look at those five aspects of of those

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five five pillars, it requires self discipline. It

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requires persistence. It's not something that you just take a

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miracle pill and and and you're done. Right? So,

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yeah, this is why it's so important not only to have medical

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doctors to tell you what you have to do and to do the prescriptions and

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and the interpretation of the results, but you also need health

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coaches to help you implement those changes into your

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daily life and turn them into habits. Because otherwise,

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it's just going to stress you out like crazy because you know there are some

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things that are not right with you. But since you don't apply anything and you

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don't do anything to change that, it's going to generate more stress than

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than not knowing about it. Got it. So, you know, as

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you take a look at potential opportunities, give me an

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example of of, like, what a 2060

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Halo Foundation, you know, founding tech

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company that's affiliated with you. Would you guys put some seed money

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into it, dollars $2.50, dollars 5 hundred? Would you go and help him

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get a grant from some government that might be trying

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to solve this and you kind of become like the the poster

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child for for that. What what what are some of the ways that

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interacting or being a part of this work would work? So yeah. So so

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so what we'll do is, present the

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the, the startup to our community of investors,

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and some of them are going to be interested

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in the opportunity. And then we're going to assist

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the the startup until they raise the the necessary amount

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of money for for their their startup. So that that's how it

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works. And and and and by the way, the

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foundation is not there to make money just as you are saying. So we are

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just, offering as much visibility as possible to the startups

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and helping them raise funds, and there is no sort of business model

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associated with that. We don't take any commission, any success fee,

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absolutely nothing. We are just going to be very happy if that

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start up, is going into the market and increasing the

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likelihood that one treatment really works in longevity. And

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then there's going to be a whole new wave

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of investments once we have one drug that extends, say,

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lifespan by five to seven years. Rapamycin was one of the

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the candidates is one of the candidates we've had but four minutes at

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some point. So there are different candidates. I'm sure that more,

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sooner or later, one of them is going to work.

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This is Pete Moore. Here's the last tip for you of the podcast.

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343
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344
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345
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347
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348
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gotta get these products in there before these workout recovery and spas

349
00:21:46,210 --> 00:21:50,025
end up saturating your market, having your members walk out of the club

350
00:21:50,025 --> 00:21:53,625
and going into one of their locations for $200 per

351
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month where they're paid 39 to you. Let's become an

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00:22:15,600 --> 00:22:19,445
and sweating, and the recovery should be just as good as the workout.

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Couple of quick questions here before we, before we, close

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out. One is, given where you sit in France

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and probably have a better lens on what other countries are

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doing versus in The US, we kinda look at ourselves and don't really go

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outside of our own box as much as we should. What country do you

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think has the best policies,

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lifestyles, you know, inertia

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to be like the longevity, you know, epicenter of the

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world? Yeah. So, unfortunately,

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I don't think it's United States. I don't think it's France nor

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Europe. I think of one specific country, Singapore.

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Singapore has one of the lowest, fertility rates in the

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world. And they they're wealthy,

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but their population is aging quickly. So they have

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this sort of emergency to fix this, a

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health span problem. And they are putting huge resources

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because they have them and because it's very urgent for them to to take

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care of this public health problem.

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So I I it's really I'm really betting on on Singapore as one

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of the, like, you know, the first and foremost countries

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that are able to, extend, people's lifespan

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and health spends at the at the national

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level. Gotcha. And then, you know, about

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seven years ago, I went to a, Clinton, president,

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Clinton, health matters conference, and he asked all the

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insurance company CEOs what's the biggest issue in the health care

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industry. And the and the the the top answer for a guy named Bruce

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Bouchard at Humana was loneliness is the biggest issue. If I could

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solve loneliness and get people out of their own heads and

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actually get them physically with other people, one, their behavior

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seems to kinda monitor you know, normalize where they're

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not necessarily, you know, sitting on a couch and and eating a

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lot of, a lot of ice cream and getting depressed about their

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weight or themselves or their relationships. What what do you

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see as the key driver or drivers on the

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longevity side? Yeah. So so as I said,

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health, mental health is one of the five pillars

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I have listed, earlier, and it's so important

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especially for older people. And there's there's this

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observation that if you, for example, if you have an accident,

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like, for example, a fracture or something, then you isolate

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yourself. And then because you isolate yourself, you're going to

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have a whole set of consequences, which eventually

401
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decreases your your your health span because of that. So it's

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so important for, people to keep very healthy

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and reach, the social ties.

404
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Gotcha. Alright. Great. Well, look. We look forward to having

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00:25:19,179 --> 00:25:23,020
you, dedicate yourself to this industry. You've now

406
00:25:23,020 --> 00:25:26,700
been exposed to the to the halo sector. And, as,

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00:25:26,940 --> 00:25:30,635
as people come up with new ideas and wanna bounce them by

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00:25:30,635 --> 00:25:33,995
2060, you know, please get in touch with Gabriel. All of his information will be

409
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out there. I look forward to, to be having you as a thought leader and

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00:25:37,355 --> 00:25:40,815
action leader, in in the network. So so welcome, Morric.

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Yeah. Thank you again very much for having me here. It's why I was really

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excited to, introduce to you guys,

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00:25:47,410 --> 00:25:51,170
2060.life, which is the website of the foundation. Please

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00:25:51,170 --> 00:25:55,010
join me if interested, and let's build a future together, a future where

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00:25:55,010 --> 00:25:58,785
people are living longer and healthier. Awesome. Alright, man.

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Go halo. Go France.